争霸8官方入口

争霸8官方入口:争霸8官方入口

College of Biological Science and Engineering

翁祖铨

发布日期:2020-10-08 发布者:生工学院

姓名:翁祖铨

性别:男

职称:教授

学历:博士

电话:

电子邮件: wengzq@fzu.edu.cn

研究方向:智能医学、生物医药、食品药品安全性评价

教育工作经历:

1998年—2003年 福建医科大学,医学学士学位

2003年—2009年 日本国立大阪大学,医学博士学位

2009年—2011年 日本独立行政法人劳动安全卫生综合研究所 研究员

2012年—2015年  美国FDA国家毒理研究中心访问学者

2015年—         争霸8官方入口 争霸8官方入口 教授

教学简介:

讲授研究生课程:《天然活性分子的功能与健康》、《现代仪器分析》

讲授本科生课程:《药理学》、《食品生物技术》

科研简介:

翁祖铨,日本国立大阪大学医学博士,十四届全国人大代表,福建省“闽江学者”特聘教授,争霸8官方入口教授,博士生导师。主持或承担多项日本厚生劳动。牟渴。拦鶩DA的研究课题,中国国家自然基金,国家卫计委福建省卫生教育联合攻关计划项目,省部级重大、重点课题,省自然科学基金,重大横向课题等二十余项。发表高水平文章80余篇,合著科技专著3篇,申请国家发明专利18项,授权10项。

主要致力于研究:

(1)医疗大数据挖掘、药物AI设计与相互作用、智能检测诊断及预测;

(2)食品、药品、环境物质的安全检测技术开发和风险性评价;

(3)环境及宿主微生物的大数据分析及相关应用与机理研究;

(4)天然活性分子的功效作用及其机理研究。

社会兼职:

1) 日本独立行政法人劳动安全卫生综合研究所客座研究员;

2) 中国营养学会公共营养分会常务委员;

3) 中国工业毒理学会委员;

4) 中国环境诱变剂学会生物标志物专业委员会委员;

5) 中国医学装备协会组织再生分会委员;

6) 福建省食品安全地方标准审评委员会委员;

7) 福建省医养结合专家;

8) 福建省生物工程学会常务理事。

科研项目:

1) 福建省重大科技项目,福建省财政厅,83020008,烧创伤大数据研究中心平台建设,在研,主持

2) 福建省科技厅, 纵向, 2021Y9155, 基于金纳米团簇/二氧化钛光催化材料的制备 及其创面抗菌作用的研究, 在研, 联合主持

3) 企业, 横向, 00802237, 痤疮丙酸杆菌小分子肽抑菌作用检测实验, 在研, 主持

4) 福建省科技厅, 纵向, 2022Y4012, 基于深度学习结合斑马鱼模式生物学早期筛查 皮肤体表病变的应用研究, 在研, 联合主持

5) 福建省自然科学基金面上项目,2020J01489,基于核酸适配体结合膜富集菌体的生物传感器构建及创面感染的精准检测,在研,主持

6) 中国国家自然科学基金委员会,面上项目,81971837,基因编辑斑马鱼促进烧伤创面修复再生的小鼠实验研究,在研,主持

7) 福建省重点项目,福建省财政厅,83020007,基于高分子材料与技术构建烧伤创面敷料,在研,主持

8) 重大横向课题,00801821,VR在烧伤救治方面的应用研究,在研,主持

9) 福州市科技计划项目,82318030,猪饲料污染物 - 玉米赤霉烯酮的检测试剂盒的研发,在研,主持

10) 福建省卫生教育联合攻关计划项目,83017000,酪氨酸激酶抑制剂类抗癌药的肝毒性分析及相关机理研究,在研,主持

11) 福州市科技计划项目,82316038,茶叶提取物-儿茶素功能性食品产业化的关键, 结题,主持

12) 闽江学者(特聘教授)基金,510246,科研启动基金,结题,主持


5年代表性论文(通讯或第一作者,包含共同):

v Da Huang; Jiahao Du; Fang Luo; Gang He; Minglang Zou; Yongming Wang; Zhenyu Lin; Decheng Wu;  Zuquan Weng ; Injectable Hydrogels with Integrated Ph Probes and Ultrasound‐Responsive Microcapsules as Smart Wound Dressings for Visual Monitoring and On‐Demand Treatment of Chronic Wounds, Advanced Healthcare Materials, 2024, 2303379: 1-12

v Chencheng Wei, Handong Wang, Gaozheng Li, Jianhua Li, Fang Zhang, Yuezhong Wu, Zuquan Weng, Multiplex detection methods for mycotoxins in agricultural products: A systematic review. Food Control 158 (2024) 110207

v Yi Zhong, Houbing Zheng, Xiaoming Chen, Yu Zhao, Tingfang Gao, Huiqun Dong, Heng Luo, Zuquan Weng, DDI-GCN: Drug-drug interaction prediction via explainable graph convolutional networks. Artificial Intelligence In Medicine 144 (2023) 102640

v Lei Fu, Zuquan Weng, Jiheng Zhang, Haihe Xie, Yiqing Cao, MMBERT: a unified framework for biomedical named entity recognition. Medical & Biological Engineering & Computing. doi: 10.1007/s11517-023-02934-8.

v Lanmei Gao, Houbing Zheng, Yuanlong Hu, Yi Zhong, Linhai Jiang, Yuanzi Wu, Fen Yan, Da Huang, Jianhua Li, Fang Zhang, Zhenyu Lin, Meishui Wang, Zuquan Weng, Fluorescent biosensor based on MB-APT combined with Pt NPs for the detection of infectious bacteria in mouse and human wounds. Sensors & Actuators: B. Chemical 393 (2023) 134318

v Binhui Wang, Da Huang, and Zuquan Weng, Recent Advances in Polymer-Based Biosensors for Food Safety Detection. Polymers (Basel). 2023 Jul 30;15(15):3253. doi: 10.3390/polym15153253.

v Wenya Ke, Juan Huang, Yi Zhong, Yuhong Shi, Fen Yan, Da Huang, Yuanzi Wu, Houbing Zheng, Zuquan Weng, Hydroxypropyl-beta-Cyclodextrin embedded resveratrol regulates gut microbiota to prevent NAFLD via activating AMPK signaling pathway. Food Bioscience 54 (2023) 102907

v Xiaoming Chen, Ying Xue, XiaoyanWu, Yi Zhong, Huiying Rao, Heng Luo, and ZuquanWeng, Deep Learning-Based Systemfor Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images. Transl Vis Sci Technol. 2023 Jan 3;12(1):29. doi: 10.1167/tvst.12.1.29.

v Chaowei Li, Wanglin Duan, Ye Zhu, Guanying Li, Min Gao, Zuquan Weng*, Yuan Zhu*, and Yazhong Bu*,Cohesion Design-Led Tough Sealants with Controllably Dissolvable Properties. ACS Applied Materials&Interfaces. 2022, 14, 30, 34415–34426

v Chenlan Xu, Shuting Chen, Cuiping Chen, Yangcan Ming, Jiahao Du, Jinyi Mu, Fang Luo, Da Huang, Na Wang, Zhenyu Lin, ZuquanWeng, Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy. International Journal of Pharmaceutics, 2022, Volume 623, 121884

v Huiqun Dong, Jia You, Yu Zhao, Danhua Zheng, Yi Zhong, Gaozheng Li, Zuquan Weng,* Heng Luo,* and Shan Jiang*, Study on the Characteristics of Small-Molecule Kinase Inhibitors-Related Drug-Induced Liver Injury. Front Pharmacol. 2022; 13: 838397.

v Ke Li, Yi Wang, Yujia Liu, Wangbiao Li, Zuquan Weng,* Hui Li, Youwu He, Zhifang Li*, Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal-polarization-gating optical coherence tomography. Journal of Biophotonics, 2022, https://doi.org/10.1002/jbio.202200098

v Yu Zhao, Rusen Zhang, Yi Zhong, Jingjing Wang, Zuquan Weng*, Heng Luo* and Cunrong Chen*, Statistical Analysis and Machine Learning Prediction of Disease Outcomes for OVID-19 and Pneumonia Patients. Front. Cell. Infect. Microbiol., 19 April 2022 Sec. Virus and Host, https://doi.org/10.3389/fcimb.2022.838749

v Yuehan Zhang, Chencheng Wei, Yi Zhong, Handong Wang, Heng Luo & Zuquan Weng, Deep learning detection of shrimp freshness via smartphone pictures. Journal of Food Measurement and Characterization, 21 June 2022

v Yuanzi Wu, Shuigen Wu, Shanyun Ma, Fen Yan, and Zuquan Weng,Cytocompatible Modification of Thermoresponsive Polymers on Living Cells for Membrane Proteomic Isolation and Analysis. Analytic chemistry. 2019 Mar 5;91(5):3187-3194.

v Tingfang Gao, Yuhong Shi,| Ying Xue, Fen Yan, Da Huang, Yuanzi Wu*, Zuquan Weng*. Polyphenol extract from superheated steam processed tea waste attenuates the oxidative damage in vivo and in vitro. J Food Biochem. 2019 Nov 6:e13096. doi: 10.1111/jfbc.13096.)

v Shuting Chen, Jie Wu, Qiang Tang, Chenlan Xu, Yan Huang, Da Huang, Fang Luo, Yuanzi Wu, Fen Yan, Zuquan Weng, Shaoyun Wang. Nano-micelles based on hydroxyethyl starch-curcumin conjugates for improved stability, antioxidant and anticancer activity of curcumin. Carbohydr Polym. 2020 Jan 15;228:115398. doi: 10.1016/j.carbpol.2019.115398. Epub 2019 Sep 30.

v Zuquan Weng, Yuhong Shi, Megumi Suda, Yukie Yanagiba, Toshihiro Kawamoto, Tamie Nakajima, Rui-Sheng Wang, Inhalation Exposure to Low Levels of Ethyl tertiary Butyl Ether: Its Genetic Effects Were Significantly Modified by ALDH2 Activity. Environ Mol Mutagen. 2019 Mar;60(2):145-153.

v Wang H, Chen J, Suda M, Yanagiba Y, Weng Z, Wang RS. Acute inhalation co-exposure to 1,2-dichloropropane and dichloromethane cause liver damage by inhibiting mitochondrial respiration and defense ability in mice. J Appl Toxicol. 2019 Feb;39(2):260-270. doi: 10.1002/jat.3715.

v Liping Lin, Chenlan Xu, Yuehan Zhang, Zuquan Weng, Rui-Sheng Wang, ALDH2 deficiency significantly exacerbates tertiary butyl alcohol-induced toxicity in mice. J Appl Toxicol. 2020 Jul;40(7):979-990. doi: 10.1002/jat.3957. Epub 2020 Feb 14.

v Xiaobin Liu, Danhua Zheng, Yi Zhong, Zhaofan Xia, Heng Luo, and Zuquan Weng, Machine learning prediction of oral drug-induced liver injury (DILI) via multiple features and endpoints. Biomed Res Int. 2020 May 19;2020:4795140. doi: 10.1155/2020/4795140.

v Shanshan Wang, Hufei Wang, Yanqiu Chen, Jilai Liu, Xiaozhen He, Da Huang, Yuanzi Wu, Yonghai, Chen, Zuquan Weng,The Protective Effects of EGCG and Curcumin against Acrylamide-induced Toxicity in Human Lymphocytes and Zebrafish Embryos. Toxicological & Environmental Chemistry. 2021, 103, 199-218, https://doi.org/10.1080/02772248.2021.1951731.

v Yanqiu Chen, Mei Wan, Yi Zhong, Tingfang Gao, Yuehan Zhang, Fen Yan, Da Huang, Yuanzi Wu, Zuquan Weng,Partially Hydrolyzed Guar Gum Modulates Gut Microbiota, Regulates the Levels of eurotransmitters and Prevents CUMS-Induced Depressive-like Behavior in Mice. Mol Nutr Food Res. 2021 Jun 14:e2100146. doi: 10.1002/mnfr.202100146.

v Xiao Chen, Mingfeng Weng, Maojin Lan 1, Zuquan Weng*, Jian Wang, Longhua Guo, Zhenyu Lin, Bin Qiu*. Superior antibacterial activity of sulfur-doped g-C3N4 nanosheets dispersed by Tetrastigma hemsleyanum Diels & Gilg's polysaccharides-3 solution. Int J Biol Macromol. 2021 Jan 31;168:453-463. doi: 10.1016/j.ijbiomac.2020.11.155.

v Yongxu Lin, Juan Huang, Tingfang Gao, Yuanzi Wu, Da Huang, Fen Yan and Zuquan Weng*, Preliminary Study on Hepatoprotective Effect and Mechanism of (-)-Epigallocatechin-3-gallate against cetaminophen-induced Liver Injury in Rats. June 2020, Iranian Journal of Pharmaceutical Research (2021), 20 (3): 46-56

获奖情况:

1) 2012年获得日本第82届卫生学会年度总会议最优秀论文奖;

2) 2015年11月被授予福建省“闽江学者”特聘教授称号;

3) 2016年5月被评为2015-2016学年争霸8官方入口创新创业活动优秀指导教师;

4) 2017年4月获得争霸8官方入口青年五四奖章;

5) 2018年福建省大学生创新创业训练计划项目优秀指导教师;

6) 2018年8月第三届全国大学生生命科学创新创业大赛指导教师一等奖;

7) 2019年度第二届争霸8官方入口“福能奖教金”获得者;

8) 2019年争霸8官方入口2019届优秀本科生毕业设计(论文)指导教师;

9) 2020年度争霸8官方入口志愿服务项目优秀指导老师;

10) 2021年度争霸8官方入口“厦航奖教金”获得者;

11) 2022年福建省科技进步二等奖;

其他


争霸8官方入口官方(中国)官方网站IOS/安卓通用版/手机APP